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AI seems to always play Isochron Sceptre but not exile a card with it.

The imprint part of Isochron Scepter is a "May" ability. In testing, an AI with all forests in its deck will always cast Isochron Scepter as soon as it can and exile nothing. I assume in your game it simply had no instant cards with CMC 2 or less.

I don't really think this is a bug since all of that is correct. More like this is an AI improvment request concerning how it uses the spell. Here is the AI improvement thread.

Improved AI code and unified card choice with other similar cards as 56ba289

Still played it without exiling anything (and cast Lightning Bolt in response to casting it).

Made it only encourage the AI if it exiles a card to it, not just that it has an exileable card in hand as it casts it in 34cc4a0.